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STABILITY OF A STOCHASTICALLY PERTURBED MODEL OF INTRACELLULAR SINGLE-STRANDED RNA VIRUS REPLICATION

2019

Compared to the replication of double-stranded RNA and DNA viruses, the replication of single-stranded viruses requires the production of a number of intermediate strands that serve as templates for the synthesis of genomic-sense strands. Two theoretical extreme mechanisms for replication for such single-stranded viruses have been proposed; one extreme being represented by the so-called linear stamping machine and the opposite extreme by the exponential growth. Of course, real systems are more complex and examples have been described in which a combination of such extreme mechanisms can also occur: a fraction of the produced progeny resulting from a stamping-machine type of replication that…

92D30 (primary) 34D20 60H10 (secondary)0209 industrial biotechnologyVirus dynamicsDynamical Systems (math.DS)02 engineering and technology03 medical and health scienceschemistry.chemical_compoundMathematical model020901 industrial engineering & automationReplication (statistics)Viral replicationFOS: MathematicsMathematics - Dynamical SystemsViral evolution030304 developmental biologySingle-Stranded RNA51ssRNA virusLyapunov function0303 health sciencesViral mutationsLyapunov methodEcologyApplied MathematicsRNAGeneral MedicineAgricultural and Biological Sciences (miscellaneous)Cell biologyStochastic modelViral replicationchemistryViral evolutionStabilityIntracellularDNAJournal of Biological Systems
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